The Top 5 GLP‑1 Weight Loss Supplements for Women — And the One I Told My Best Friend to Buy
GLP‑1 supplements have taken over the weight loss world, but not all are created equal. We compared formulas, delivery tech, and results so you don’t waste your money and time on the wrong one.
Fig 1. Visual simulation: How BHB Salts (red) react upon contact with dense visceral fat cells.
Over the last year, GLP‑1 has emerged as the holy grail of weight loss for women in modern-day America.
It’s the hormone your body makes to help you feel full on less food — and lose weight, practically on autopilot.
When GLP‑1 levels are high, cravings fade, portions shrink, and you don’t feel like you’re depriving yourself. “Food noise” in your head quiets down.
And to make matters even better, your metabolism gets a significant boost. This sets up a “double edged” effect where you can burn more calories while you’re eating less.
tl;dr — GLP-1 makes losing weight feel effortless.
That’s probably why, in recent years, multiple celebrities have been caught boosting their GLP‑1 with outrageously expensive “off-label” injections that were designed for diabetes, not weight loss.
Many of them managed to transform their bodies, but they also started experiencing severe drug-induced side effects as a result — like diarrhea, vomiting, stomach pain, fatigue, dizziness, and confusion… not to mention rapid weight regain if they stopped the injections.
Thankfully, a new wave of natural GLP‑1 boosters has made it easier, cheaper, and safer to support healthy GLP‑1 levels — without weekly needles, harsh drugs, or horrible side effects.
But with all the brands entering the market, which ones actually work? That’s exactly what we investigated.
Our team reviewed dozens of GLP‑1 supplements and narrowed them down to the five most popular options on the market. Then we compared them for ingredient quality, delivery technology, transparency, and most importantly… effectiveness.
Here’s what we found…
How We Ranked These Supplements
We scored each product on four critical factors:
Ingredient Synergy: Do the ingredients actually work together to support appetite control, metabolic balance, and healthy GLP-1 activity?
Bioavailability & Absorption: Are the nutrients in forms your body can easily absorb and use, not cheap fillers that pass right through?
Transparency & Quality: Is the formula fully disclosed, clinically relevant, and manufactured under consistent standards?
User Feedback: Are real customers seeing meaningful changes in cravings, energy, and weight loss?
Our Top 5 GLP‑1 Weight Loss Supplements
1. Keto Spark
by Keto ACV Gummies
Total Ranking
A+
Total Ranking
Out of every GLP‑1 supplement we reviewed, GL-ME™ was clearly different. From the very first week of testing, it left the other supplements in the dust.
Our reviewers consistently reported feeling fuller after smaller meals, more energetic throughout the day, and far more in control of themselves around snacks. As the weeks went on, many began to visibly lose weight.
And it all happened without any considerable effort on their part. Just take 2 capsules and go on about your day. Multiple testers described this experience as “life-changing.”
And most telling of all… most of our testers continued using the supplement after the test period was over. This wasn’t true for any other supplement on the list. Only GL-ME™.
The difference came down to more than just ingredient count — GL-ME’s formula is carefully balanced, backed by a mountain of research, and delivered in a way that keeps it working for hours.
In short: If you want the supplement that checks every box for effectiveness, safety, and ease of use, GL-ME™ is the clear winner.
Special Offer: GL-ME™ Is Offering Up to 50% OFF for Our Readers (Limited Supply)
Why it’s #1
Balanced, synergistic formula — Includes berberine, prebiotics, probiotics, green tea EGCG, cinnamon, and bitter melon. All these ingredients combine to create optimum conditions for natural GLP-1 production and healthy metabolic balance
Prebiotics & probiotics — Most GLP-1 supplements completely miss this crucial combination — yet it’s the most studied, science-backed way to naturally boost GLP-1. GL-ME includes both, supporting the gut bacteria directly responsible for GLP-1 release, appetite control, and smoother digestion.
Metabolism support — GL-ME combines compounds shown in research to influence key metabolic regulators such as AMPK and insulin sensitivity. This helps the body burn stored fat more effectively and maintain a healthier, more efficient metabolism over time.
Full transparency — Every ingredient and dose is clearly listed. It is professionally formulated and manufactured under strict quality standards from start to finish
PROS
- Most complete and balanced formula in the category
- Includes prebiotics, probiotics, and berberine
- Supports metabolic function for steady, sustained results
- Transparent manufacturing and testing
- 60-Day, No-Hassle, Money Back Guarantee
CONS
- Stock often sold out due to going viral on social media.
- Available only on the official website (beware of fakes on Amazon).
Our experience: Testers reported calmer cravings within the first week, more stable energy, and noticeably better control around snacks. Over several weeks, clothes fit looser and the “food noise” in their heads was quieter.
Bottom line: GL-ME™ offers the strongest combination of the right ingredients, in the right balance. And the results show it. GL-ME™ GLP-1 Booster is the clear winner, hands down.
Special Offer: GL-ME™ Is Offering Up to 50% OFF for Our Readers (Limited Supply)
1. Keto Spark
by Keto ACV Gummies
A+
Overall Grade
2. Leptozan
by Zonata
Total Ranking
B+
Total Ranking
ColonBroom has gained popularity for its clean, plant-forward formula and focus on digestion and appetite regulation. It includes ingredients like berberine, L-glutamine, and hibiscus, which have been linked to gut health, metabolism, and appetite control. Most users notice lighter digestion and reduced bloating within the first few weeks.
However, ColonBroom lacks prebiotics and probiotics, two of the most researched components for supporting GLP-1 production. It also doesn’t include any direct metabolic activators beyond berberine, meaning results may be more subtle compared to multi-pathway formulas like GL-ME.
It also includes L-glutamine, which is beneficial for overall digestive function and nutrient absorption — a strong addition — but a surprising choice was to combine it with bupleurum and hibiscus, as this trio can occasionally cause mild digestive discomfort in sensitive users. This isn’t a major concern for most, but it’s worth noting for those prone to stomach sensitivity.
PROS
- Includes berberine and L-glutamine for digestion and metabolic balance
- Plant-based formula with natural appetite and bloating support
- Transparent, straightforward ingredient profile
CONS
- Stock often sold out due to going viral on social media.
- Available only on the official website (beware of fakes on Amazon).
- Available only on the official website (beware of fakes on Amazon).
Verdict: A clean, well-rounded option for basic digestive health and mild appetite support. It includes credible ingredients like berberine and L-glutamine, but without prebiotics, probiotics, or advanced metabolic activators, it falls short of the full GLP-1 and metabolism support seen in more complete formulas like GL-ME™.
2. Leptozan
by Zonata
B+
Overall Grade
3. FitSpresso
by FitSpresso
Total Ranking
B-
Total Ranking
HUM has built a strong reputation for promoting digestive comfort and reducing bloating. Its formula combines a broad enzyme blend that helps break down proteins, fats, and carbohydrates, along with soothing botanicals like ginger, fennel, and peppermint to support smoother digestion and post-meal comfort. Many users notice a less bloated feeling within the first few weeks — a clear sign it’s doing its job on the digestive front.
That said, HUM isn’t designed to target GLP-1 activity or metabolism directly. It doesn’t include key GLP-1–linked ingredients such as berberine, prebiotics, or probiotics, so its effects stay focused on digestion rather than hunger control or metabolic balance.
PROS
- Includes berberine and L-glutamine for digestion and metabolic balance
- Plant-based formula with natural appetite and bloating support
- Transparent, straightforward ingredient profile
- 60-Day, No-Hassle, Money Back Guarantee
CONS
- Stock often sold out due to going viral on social media.
- Available only on the official website (beware of fakes on Amazon).
- Available only on the official website (beware of fakes on Amazon).
Verdict: A solid pick for easing bloating and supporting digestion, but not designed for those looking to influence GLP-1 or metabolic activity.
3. FitSpresso
by FitSpresso
B-
Overall Grade
4. LipoVive
by Fusa Nutrition LLC
Total Ranking
C+
Total Ranking
Inno Shred is built for fast metabolic activation and energy support. It includes berberine, chromium, and InnoSlim® (ginseng + astragalus) for glucose control, alongside caffeine and theobromine for a strong energy boost. Many users feel more active and focused soon after taking it.
However, it’s more of a stimulant-driven formula than a true GLP-1 support supplement. It lacks prebiotics and probiotics, so appetite and hormone balance aren’t its main strengths.
Because it’s caffeine-heavy, some users may experience jitters or restlessness, though this depends on individual tolerance.
PROS
- Includes berberine and L-glutamine for digestion and metabolic balance
- Plant-based formula with natural appetite and bloating support
- Transparent, straightforward ingredient profile
- 60-Day, No-Hassle, Money Back Guarantee
CONS
- Stock often sold out due to going viral on social media.
- Available only on the official website (beware of fakes on Amazon).
- Available only on the official website (beware of fakes on Amazon).
Verdict: A solid choice for those prioritizing energy and metabolic support. Inno Shred delivers quick, noticeable effects through its stimulant blend, but since it doesn’t target GLP-1 or gut health, it’s better viewed as a short-term metabolism and energy enhancer rather than a complete appetite or hormonal balance solution.
4. LipoVive
by Fusa Nutrition LLC
C+
Overall Grade
5. CurcuminMD® Plus
by NutraVibe
Total Ranking
C-
Total Ranking
Lemme GLP-1 Daily takes a minimalist approach, using a trio of fruit and botanical extracts aimed at supporting appetite control and metabolic balance. The formula features Morosil™ red orange extract, Eriomin® lemon extract, and Supresa® saffron, each backed by emerging research on mood, satiety, and metabolic health. Users often describe feeling calmer around food and noticing smaller portion sizes within the first few weeks.
However, it’s a light, lifestyle-oriented formula, not a full-spectrum GLP-1 support supplement. It lacks core metabolic and gut-health ingredients such as berberine, prebiotics, and probiotics — so while it may help reduce cravings, it’s less likely to influence long-term GLP-1 activity or metabolism on its own.
PROS
- Includes berberine and L-glutamine for digestion and metabolic balance
- Plant-based formula with natural appetite and bloating support
- Transparent, straightforward ingredient profile
- 60-Day, No-Hassle, Money Back Guarantee
CONS
- Stock often sold out due to going viral on social media.
- Available only on the official website (beware of fakes on Amazon).
- Available only on the official website (beware of fakes on Amazon).
Verdict: A clean, easy-to-take option for gentle appetite and mood support, though it lacks the metabolic depth of more complete GLP-1 formulas.
5. FitBurn
by NutraVibe
C-
Overall Grade
Compare The Top 5 Weight Loss Solutions
Why the new "Gummy Technology" is winning in 2025
(Gummies)
Keto Spark
#1 Winner
Leptozan
FitSpresso
LipoVive
FitBurn
“Thousands of people have already experienced life-changing results—and now, it’s your turn! Don’t settle for band-aid solutions when real transformation is within reach.”
Why GL-ME™ Took the #1 Spot
While other products target pieces of the GLP-1 puzzle, GL-ME™ brings them all together in one science-driven capsule:
The Right Ingredients — Covers metabolic control (berberine, green tea, bitter melon), appetite signaling (chromium, cinnamon), and gut health (pre + probiotics + digestive enzymes).
The Right Balance — No stimulants or fillers, just bioavailable nutrients that work synergistically.
The Right Standards — Transparent label, clinical-grade extracts, expert formulation, and stringent quality control.
The Right Effect — A “double-edge” approach of feeling less hungry + having enhanced metabolism support.
The Right Results — Our testers report more energy, easier digestion, and noticeable slimming within weeks. This matches the reports from thousands of current customers as well.
Why You Should Ditch Quick-Fix Diets for GLP-1 Support Supplements
Strict diets and calorie restriction fight your body’s natural signals — leaving you tired, hungry, and stuck in a cycle of yo-yo weight gain.
On top of that, modern stress and nutrient-poor foods can actively suppress your GLP-1 response, triggering even more overeating and fat storage. That’s why supporting healthy GLP-1 levels can help reset those signals so you finally feel in control again.
GLP-1 support supplements work with your body’s own metabolic system to help you effortlessly eat less. No willpower or feelings of deprivation required.
The GLP‑1 Supplements Buying Guide (So You Don’t Get Burned)
Things to Look For
Research‑Backed Ingredients — Berberine, EGCG, chromium, cinnamon, bitter melon.
Added Gut Support — Probiotics and prebiotics for gut–brain communication and optimum GLP-1 production.
Clinical-Grade Formulation — Optimized ingredient rations and bioavailable forms
Full Label Transparency — No secretive proprietary blends without the ingredients spelled out
Money-Back Guarantee — It’s important that the company stands by their product, and you risk nothings by trying it.
Red Flags to Avoid
Stimulant-heavy “fat burners” that leave you jittery
Missing gut balance ingredients for optimized GLP‑1 support
Secretive formulations with hidden ingredients, undisclosed doses, and likely fillers
Overhyped claims without any proof they’re true
Are GLP‑1 Supplements Really the Answer?
No supplement is a magic bullet, but the right GLP-1 support formula can make a profound difference in your hunger, energy levels, and long-term weight management.
Most users feel a difference within days and see visible results within 6–8 weeks of consistent use.
Special Offer for Our Readers
We contacted the GL-ME™ team after our testing, and they agreed to extend an exclusive deal:
Up to 50% OFF select multi-bottle bundles
Free U.S. shipping on first order
90-day money-back guarantee
At this price — with zero risk — it’s the perfect time to experience how supporting your own GLP-1 can help you reclaim your body and confidence.
⭐⭐⭐⭐⭐
Basead on 3732 Reviews of
KETO SPARK
- Burns Fat Not Carbs
- Helps Suppress Appetite
- Consistent Energy Without Crashes
- More Palatable Pills, Capsules, Powders
- Long-lasting Results for Sustainable Weight Loss
- Gentle on Stomach Acids & Digestion
“Thousands of people have already experienced life-changing results—and now, it’s your turn! Don’t settle for band-aid solutions when real transformation is within reach.”
Why Did Keto Spark Win the Battle of 2025?
Our analysis makes one thing clear: while the idea of gelatine has merit, science has moved on.
While products like Leptozan (#2) masterfully bring GLP-1 science to the table, Keto Spark (#1) won our battery of tests by delivering the fastest results through Ketosis, while maintaining the convenience of a chewable gummy.
It is the true evolution of the “gelatine trick” everyone was looking for, without the kitchen mess and with proven results.
Seen enough? Go back to Top 1 and secure the winning technology before it sells out.
“Thousands of people have already experienced life-changing results—and now, it’s your turn! Don’t settle for band-aid solutions when real transformation is within reach.”
⭐⭐⭐⭐⭐
Basead on 3732 Reviews of
KETO SPARK
Frequently Asked Questions
Is Keto Spark really better than the homemade "Gelatine Trick"?
Yes. While the viral “gelatine trick” relies on slow digestion to release amino acids, Keto Spark is formulated with pure BHB Salts in a gummy delivery system. This allows for immediate absorption into the bloodstream, triggering Ketosis (fat burning) much faster and more efficiently than ordinary supermarket gelatine ever could.
How long does it take to see results?
Most users report a surge in mental energy and reduced cravings within the first 24 hours. Visible physical changes, such as a reduction in bloating and visceral fat measurements, typically begin to appear between 7 to 14 days of consistent use.
Do I need to follow a strict diet or exercise plan?
Keto Spark is designed to “hack” your metabolism to burn fat for energy, even at rest. While a healthy lifestyle accelerates results, the formula works independently to keep your body in a fat-burning state, making it ideal for those with busy schedules who can’t spend hours at the gym.
Are there any side effects?
Keto Spark is made from natural ingredients and is free from harsh stimulants often found in other fat burners (like excessive caffeine). It is generally well-tolerated. However, as with any supplement, if you are pregnant, nursing, or have a medical condition, we recommend consulting your GP before starting.
What happens if it doesn't work for me?
You are fully protected. The manufacturer offers a 60-Day Money-Back Guarantee. If you don’t see the mirror results you expect, simply contact their support team for a full refund. It’s a risk-free investment in your transformation.
“Thousands of people have already experienced life-changing results—and now, it’s your turn! Don’t settle for band-aid solutions when real transformation is within reach.”